Article
Platelet glycoprotein receptor IIIa polymorphism PLA1/PLA2 and coronary risk: a meta-analysis.
Thrombosis and haemostasis - 1 Apr 2001
Di Castelnuovo A, de Gaetano G, Donati M B, Iacoviello L
Abstract excerpt
Membrane glycoprotein IIb/IIIa plays a major role in platelet function. The gene encoding the glycoprotein IIIa shows a common polymorphism PLA1/PLA2 that was variably associated with vascular disease. To clarify the role of PLA1/PLA2 polymorphism in coronary risk, a meta-analysis of published data was conducted. Studies were identified both by MEDLINE searches, and hand searching of journals and abstract books....
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