Article
Glycoprotein IIIA gene (PlA) polymorphism and aspirin resistance: is there any correlation?
The Annals of pharmacotherapy - 1 Jun 2005
Papp Elod, Havasi Viktoria, Bene Judit, Komlosi Katalin, Czopf Laszlo, Magyar Eva, Feher Csaba, Feher Gergely, Horvath Beata, Marton Zsolt, Alexy Tamas, Habon Tamas, Szabo Levente, Toth Kalman, Melegh Bela
Abstract excerpt
BACKGROUND: Platelet glycoprotein (GP) IIb/IIIa receptors play an inevitable role in platelet aggregation. The GP IIIa gene is polymorphic (PlA1/PlA2) and the presence of a PlA2 allele might be associated with an increased risk for acute coronary syndrome (ACS). OBJECTIVE: To examine the prevalence of the PlA2 allele in patients with ACS and in subjects with or without aspirin resistance. METHODS: The prevalence...
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