Article
Glycoprotein IIIa polymorphism and risk of myocardial infarction.
Cardiovascular research - 1 Mar 1997
Samani N J, Lodwick D
Abstract excerpt
OBJECTIVES: To prospectively investigate whether the PlA2 variant of the platelet adhesion molecule glycoprotein IIIa influences the risk of myocardial infarction. BACKGROUND: The platelet glycoprotein IIb/IIIa receptor plays an important role in platelet aggregation. The IIIa polypeptide is polymorphic due to a single base change at position 1565 resulting in either proline PlA1 or leucine PlA2 at position 33 in...
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