Article
COX23, a homologue of COX17, is required for cytochrome oxidase assembly.
The Journal of biological chemistry - 23 Jul 2004
Barros Mario H, Johnson Alisha, Tzagoloff Alexander
Abstract excerpt
Deletion of reading frame YHR116W of the Saccharomyces cerevisiae nuclear genome elicits a respiratory deficiency. The encoded product, here named Cox23p, is shown to be required for the expression of cytochrome oxidase. Cox23p is homologous to Cox17p, a water-soluble copper protein previously implicated in the maturation of the Cu(A) center of cytochrome oxidase. The respiratory defect of a cox23 null mutant is...
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