Article
Cmc1p is a conserved mitochondrial twin CX9C protein involved in cytochrome c oxidase biogenesis.
Molecular and cellular biology - 1 Jul 2008
Horn Darryl, Al-Ali Hassan, Barrientos Antoni
Abstract excerpt
Copper is an essential cofactor of two mitochondrial enzymes: cytochrome c oxidase (COX) and Cu-Zn superoxide dismutase (Sod1p). Copper incorporation into these enzymes is facilitated by metallochaperone proteins which probably use copper from a mitochondrial matrix-localized pool. Here we describe a novel conserved mitochondrial metallochaperone-like protein, Cmc1p, whose function affects both COX and Sod1p. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
