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Article

Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase.

The Journal of biological chemistry - 25 Oct 2002

Nobrega Marina P, Bandeira Simone C B, Beers John, Tzagoloff Alexander

Abstract excerpt

COX19, a nuclear gene of Saccharomyces cerevisiae, was cloned by transformation of a respiratory-deficient mutant from complementation group G188 of a pet mutant collection. The gene codes for an 11-kDa protein (Cox19p) required for expression of cytochrome oxidase. Because cox19 mutants are able to synthesize the mitochondrial and nuclear gene products of cytochrome oxidase, Cox19p probably functions...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12171940
DOI: 10.1074/jbc.M207348200

Genes

COX19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase.PMID 12171940Read ↗

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Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment.Semantic proximity Read ↗

COX23, a homologue of COX17, is required for cytochrome oxidase assembly.Semantic proximity Read ↗

Cox17 is functional when tethered to the mitochondrial inner membrane.Semantic proximity Read ↗

Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development.Semantic proximity Read ↗

Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.Semantic proximity Read ↗

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COX10 codes for a protein homologous to the ORF1 product of Paracoccus denitrificans and is required for the synthesis of yeast cytochrome oxidase.Semantic proximity Read ↗

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