Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin-like growth factor 1 promoter polymorphism influences insulin gene variable number of tandem repeat-associated risk for juvenile onset type 1 diabetes.

Tissue antigens - 1 Jun 2004

Eerligh P, Roep B O, Giphart M J, Koeleman B P C

Abstract excerpt

Insulin-like growth factor 1 (IGF1) plays an important role in the development and function of pancreatic beta-cells and contributes to infant growth, which we recently reported to be associated with type 1 diabetes (T1D). Here, we studied an IGF1 microsatellite in 206 families with T1D and its interaction with the polymorphism near the insulin (INS) gene variable number of tandem repeats. The IGF1 microsatellite...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IGF1 gene

Share to Genetic Predisposition to Disease

Share to Insulin

Share to Insulin-Like Growth Factor I

Share to Minisatellite Repeats

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 15140033
DOI: 10.1111/j.0001-2815.2004.00229.x

Genes

IGF1
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin-like growth factor 1 promoter polymorphism influences insulin gene variable number of tandem repeat-associated risk for juvenile onset type 1 diabetes.PMID 15140033Read ↗

Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.Semantic proximity Read ↗

Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes.Semantic proximity Read ↗

Genetic interaction among three genomic regions creates distinct contributions to early- and late-onset type 1 diabetes mellitus.Semantic proximity Read ↗

Absence of the wild-type allele (192 base pairs) of a polymorphism in the promoter region of the IGF-I gene but not a polymorphism in the insulin gene variable number of tandem repeat locus is associated with accelerated weight gain in infancy.Semantic proximity Read ↗

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.Semantic proximity Read ↗

The <i>TH01</i> microsatellite and <i>INS</i> VNTR are strongly associated with type 2 diabetes and fasting insulin secretionSemantic proximity Read ↗

Insulin gene variable number of tandem repeats (INS VNTR) genotype and metabolic syndrome in childhood obesity.Semantic proximity Read ↗

The human leukocyte antigen genotype has a modest effect on the insulin gene polymorphism-associated susceptibility to type 1 diabetes in the Finnish population.Semantic proximity Read ↗

Growth in Children with HLA-Conferred Susceptibility to Type 1 Diabetes.Semantic proximity Read ↗

The insulin-like growth factor-II receptor gene is associated with type 1 diabetes: evidence of a maternal effect.Semantic proximity Read ↗

Increased maternal Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) associated with older age at diagnosis of Type 1 diabetes in offspring.Semantic proximity Read ↗

Identification of a single nucleotide insertion polymorphism in the upstream region of the insulin promoter factor-1 gene: an association study with diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.