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Article

Insulin gene variable number of tandem repeats (INS VNTR) genotype and metabolic syndrome in childhood obesity.

The Journal of clinical endocrinology and metabolism - 1 Nov 2006

Santoro Nicola, Cirillo Grazia, Amato Alessandra, Luongo Caterina, Raimondo Paolo, D'Aniello Antonietta, Perrone Laura, Miraglia del Giudice Emanuele

Abstract excerpt

OBJECTIVE: The insulin variable number of tandem repeats (VNTR) polymorphism located in the insulin gene promoter (INS VNTR) has been associated with insulin levels in obese children. Hyperinsulinemia is a pivotal factor in the development of metabolic syndrome, an emerging complication in childhood obesity. With the present study, we aimed to test the associations between INS VNTR and the metabolic syndrome in...

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Source

Identifiers

PMID: 16868061
DOI: 10.1210/jc.2005-2705

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Insulin gene variable number of tandem repeats (INS VNTR) genotype and metabolic syndrome in childhood obesity.PMID 16868061Read ↗

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.Semantic proximity Read ↗

VNTR polymorphism of the insulin gene and childhood overweight in a general population.Semantic proximity Read ↗

INS VNTR is a QTL for the insulin response to oral glucose in obese children.Semantic proximity Read ↗

Insulin gene variable number of tandem repeats is associated with increased fat mass during adolescence in non-obese girls.Semantic proximity Read ↗

Common variants in the regulatory region of the insulin gene are associated with fasting plasma insulin levels in juvenile obesity.Semantic proximity Read ↗

Heterogeneity of class I INS VNTR allele association with insulin secretion in obese children.Semantic proximity Read ↗

The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children.Semantic proximity Read ↗

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Insulin gene polymorphism in women with polycystic ovary syndrome.Semantic proximity Read ↗

Insulin gene VNTR genotype is associated with insulin sensitivity and secretion in infancy.Semantic proximity Read ↗

Association of Insulin Gene VNTR Polymorphism with Polycystic Ovary SyndromeSemantic proximity Read ↗

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