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Article

Genetic interaction among three genomic regions creates distinct contributions to early- and late-onset type 1 diabetes mellitus.

Pediatric diabetes - 1 Dec 2005

Felner Eric I, Klitz William, Ham Melissa, Lazaro Ana M, Stastny Peter, Dupont Bo, White Perrin C

Abstract excerpt

There are two peaks in the distribution of the age of onset of type 1 diabetes mellitus (T1DM)--the first in early childhood and the second at the time of puberty. Although T1DM results from the interaction of genetic and non-genetic factors, it has not been established which factors contribute to the bimodal distribution. The genetic component of T1DM is in large part related to genes from the human leukocyte...

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Source

Identifiers

PMID: 16390390
DOI: 10.1111/j.1399-543X.2005.00132.x

Genes

INS
CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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