Article
Identification of a single nucleotide insertion polymorphism in the upstream region of the insulin promoter factor-1 gene: an association study with diabetes mellitus.
Diabetologia - 1 May 1998
Yamada K, Yuan X, Ishiyama S, Ichikawa F, Kohno S, Shoji S, Hayashi H, Nonaka K
Abstract excerpt
Insulin promoter factor 1 (IPF1) is a key factor both for the regulation of insulin gene expression and for the development of the pancreas. In this study 88 patients with non-insulin-dependent diabetes mellitus (NIDDM) who were diagnosed as diabetic at less than 40 years of age, 55 patients with insulin-dependent-diabetes (IDDM), and 67 normal control subjects were analysed for variants in the upstream region of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
