Article
Identifying polymorphisms in the Rattus norvegicus D3 dopamine receptor gene and regulatory region.
Genes, brain, and behavior - 1 Jun 2004
Smits B M G, D'Souza U M, Berezikov E, Cuppen E, Sluyter F
Abstract excerpt
The D(3) dopamine receptor has been implicated in several neuropsychiatric disorders, including schizophrenia, Parkinson's disease and addiction. Sequence variation in the D(3) gene can lead to subtle alteration in receptor structure or gene expression and thus to a different phenotype. In this study we examine the sequence variation in the D(3) gene in 96 rat strains and substrains. Interestingly, the analyses...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
