Article
Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes.
Molecular pharmacology - 1 Aug 1994
Asghari V, Schoots O, van Kats S, Ohara K, Jovanovic V, Guan H C, Bunzow J R, Petronis A, Van Tol H H
Abstract excerpt
Recent molecular characterization of the human D4 gene has revealed the existence of various polymorphic forms of this receptor. These variations are found in the putative third cytoplasmic loop region and encode a variable number of repeats of 16 amino acids in length. In the present study we ha...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cells, Cultured
- DNA Primers
- Humans
- Molecular Sequence Data
- Mutation
- Polymorphism, Genetic
- Rats
- Receptors, Dopamine
- Receptors, Dopamine D2
- Receptors, Dopamine D4
- Repetitive Sequences, Nucleic Acid
- Sequence Deletion
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid