Article
Dopamine D3 receptor gene: organization, transcript variants, and polymorphism associated with schizophrenia.
American journal of medical genetics - 16 Feb 1996
Griffon N, Crocq M A, Pilon C, Martres M P, Mayerova A, Uyanik G, Burgert E, Duval F, Macher J P, Javoy-Agid F, Tamminga C A, Schwartz J C, Sokoloff P
Abstract excerpt
DNA fragments from a genomic library were used to establish the partial structure of the human dopamine D3 receptor gene (DRD3). Its coding sequence contains 6 exons and stretches over 40,000 base pairs. The complete DRD3 transcript and three shorter variants, in which the second and/or third exon are deleted, were detected in similar proportions in brains from four controls and three psychiatric patients. The...
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