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Article

Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity.

Molecular psychiatry - 1 May 2012

Tovo-Rodrigues L, Rohde L A, Roman T, Schmitz M, Polanczyk G, Zeni C, Marques F Z C, Contini V, Grevet E H, Belmonte-de-Abreu P, Bau C H D, Hutz M H

Abstract excerpt

Although several studies have demonstrated an association between the 7-repeat (7R) allele in the 48-bp variable number of tandem repeats (VNTRs) in the exon 3 at dopamine receptor D4 (DRD4) gene and attention-deficit/hyperactivity disorder (ADHD), others failed to replicate this finding. In this study, a total of 786 individuals with ADHD were genotyped for DRD4 exon 3 VNTR. All 7R homozygous subjects were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21403674
DOI: 10.1038/mp.2011.12

Genes

DRD4

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Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity.PMID 21403674Read ↗

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