Article
Identification of critical domains and putative partners for the Caenorhabditis elegans spindle component LIN-5.
Molecular genetics and genomics : MGG - 1 Jun 2004
Fisk Green R, Lorson M, Walhout A J M, Vidal M, van den Heuvel S
Abstract excerpt
Successful cell division requires proper assembly, placement and functioning of the spindle apparatus that segregates the chromosomes. The Caenorhabditis elegans gene lin-5 encodes a novel coiled-coil component of the spindle required for spindle positioning and chromosome segregation. To gain further insights into lin-5 function, we screened for dominant suppressors of the partial loss-of-function phenotype...
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