Cullin-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development.

doi:10.1002/dvdy.20322

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Article

Cullin-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2005

Ayyub Champakali, Sen Anindya, Gonsalves Foster, Badrinath Kishan, Bhandari Poonam, Shashidhara L S, Krishna Sudhir, Rodrigues Veronica

Abstract excerpt

We describe a developmental analysis of Drosophila Cullin-5 (Cul-5) identified from the genome sequence on the basis of its high degree of homology to vertebrate and worm sequences. The gene is expressed in a restricted manner in ectodermal cells throughout development suggesting pleiotropic functions. We decided to examine the phenotypes of Cul-5 aberrations in two well-studied developmental systems: the...

Topics

Amino Acid Sequence
Animals
Cell Division
Cullin Proteins
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Gene Expression
Gene Expression Regulation
Genes, Insect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Larva

Metamorphosis, Biological

Molecular Sequence Data

Mutation

Neuromuscular Junction

Neurons, Afferent

Organogenesis

Pupa

Source

Open in PubMed

Identifiers

PMID: 15712282
DOI: 10.1002/dvdy.20322

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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