Article
Cullin-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2005
Ayyub Champakali, Sen Anindya, Gonsalves Foster, Badrinath Kishan, Bhandari Poonam, Shashidhara L S, Krishna Sudhir, Rodrigues Veronica
Abstract excerpt
We describe a developmental analysis of Drosophila Cullin-5 (Cul-5) identified from the genome sequence on the basis of its high degree of homology to vertebrate and worm sequences. The gene is expressed in a restricted manner in ectodermal cells throughout development suggesting pleiotropic functions. We decided to examine the phenotypes of Cul-5 aberrations in two well-studied developmental systems: the...
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