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Article

The role of self-association in Fin1 function on the mitotic spindle.

The Journal of biological chemistry - 2 Nov 2007

Woodbury Erika L, Morgan David O

Abstract excerpt

Stabilization of spindle microtubules during anaphase is essential for proper chromosome segregation. Fin1 is a budding yeast protein that localizes to the poles and microtubules of the spindle during anaphase and contributes to spindle stability. The N-terminal half of Fin1 is phosphorylated at multiple sites by the cyclin-dependent kinase Clb5-Cdk1, and dephosphorylation in anaphase triggers its localization to...

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Identifiers

PMID: 17804403
DOI: 10.1074/jbc.M705344200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of self-association in Fin1 function on the mitotic spindle.PMID 17804403Read ↗

Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase.Semantic proximity Read ↗

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