Article
Characterization of five RNA editing sites in Shab potassium channels.
Channels (Austin, Tex.) - 1 Jan 2000
Ryan Mary Y, Maloney Rachel, Reenan Robert, Horn Richard
Abstract excerpt
RNA editing revises the genetic code at precise locations, creating single base changes in mRNA. These changes can result in altered coding potential and modifications to protein function. Sequence analysis of the Shab potassium channel of Drosophila melanogaster revealed five such RNA editing sites. Four are constitutively edited (I583V, T643A, Y660C and I681V) and one undergoes developmentally regulated editing...
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