Article
Voltage-gated potassium channels and the diversity of electrical signalling.
The Journal of physiology - 1 Jun 2012
Jan Lily Yeh, Jan Yuh Nung
Abstract excerpt
Since Hodgkin and Huxley discovered the potassium current that underlies the falling phase of action potentials in the squid giant axon, the diversity of voltage-gated potassium (Kv) channels has been manifested in multiple ways. The large and extended potassium channel family is evolutionarily conserved molecularly and functionally. Alternative splicing and RNA editing of Kv channel genes diversify the channel...
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