Article
RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation.
BMC evolutionary biology - 27 Jun 2007
Jin Yongfeng, Tian Nan, Cao Jun, Liang Jing, Yang Zhaolin, Lv Jianning
Abstract excerpt
BACKGROUND: RNA editing and alternative splicing play an important role in expanding protein diversity and this is well illustrated in studies of nicotinic acetylcholine receptors (nAChRs). RESULTS: Here, we compare the RNA editing and alternative splicing of the nAChR alpha6 subunit genes from different insects spanning ~300 million years of evolution- Drosophila melanogaster, Anopheles gambiae, Bombyx mori,...
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