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Article

Cytomegalovirus UL97 mutations associated with ganciclovir resistance in immunocompromised patients from Argentina.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2004

Sánchez Puch Silvia, Ochoa Claudia, Carballal Guadalupe, Zala Carlos, Cahn Pedro, Brunet Rosario, Salomón Horacio, Videla Cristina

Abstract excerpt

BACKGROUND: Prolonged therapy with ganciclovir (GCV) can result in the development of GCV-resistant strains due to mutations in the viral phosphotransferase (UL97 gene) and/or in the viral DNA polymerase (UL54 gene). OBJECTIVES: The purpose of this study was to detect by molecular methods the most prevalent UL97 mutants which confer ganciclovir-resistance in immunocompromised populations. STUDY DESIGN: Patients...

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Identifiers

PMID: 15135748
DOI: 10.1016/j.jcv.2003.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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