Article
HCMV UL97 phosphotransferase gene mutations may be associated with antiviral resistance in immunocompromised patients in Belém, PA, Northern Brazil.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000
Silva Dorotéa de Fátima Lobato da, Cardoso Jedson Ferreira, Silva Sandro Patroca da, Arruda Leda Mani França, Medeiros Renato Lopes Fernandes de, Moraes Marluce Matos, Sousa Rita Catarina Medeiros
Abstract excerpt
INTRODUCTION: Human cytomegalovirus is one of the causes of opportunist infections in immunocompromised patients, and is triggered by factors such as state of viral latency, weakened immune responses, and development of antiviral resistance to ganciclovir, the only drug offered by the public health system in Brazil to treat the infection. The goal of this study was to identify mutations that may be associated...
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