Article
Cytomegalovirus UL97 ganciclovir resistance mutations in kidney transplant recipients.
Bratislavske lekarske listy - 1 Jan 2022
Tasoujlu Mina, Khalafkhany Davod, Makhdoomi Khadijeh, Motazakker Morteza
Abstract excerpt
OBJECTIVES: Widespread and prolonged therapy with ganciclovir (GCV) may result in the emergence of GCV-resistant mutations in human cytomegalovirus (HCMV) genome. The aim of this study was to detect the UL97 mutations associated with GCV resistance in kidney transplant recipients. METHODS: Forty-nine kidney recipients with positive HCMV DNAemia, who received GCV therapy were included in this study. A 707 bp...
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