Article
The emergence of cytomegalovirus resistance to ganciclovir therapy in kidney transplant recipients.
International immunopharmacology - 20 Dec 2006
Nogueira Eliana, Ozaki Kikumi S, Tomiyama Helena, Granato Celso F H, Camara Niels O S, Pacheco-Silva Alvaro
Abstract excerpt
Transplant recipients that have not been previously exposed to the cytomegalovirus (CMV) are highly susceptible to viral diseases while under immunosuppression therapy. CMV disease requires prolonged therapy, facilitating the emergence of resistant strains. Persistence of positive antigenemia represents clinical evidence of the presence of resistant strains, although its frequency is unknown. These strains may...
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