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Microsatellite Instability and Altered Expressions of MLH1 and MSH2 in Gastric Cancer

1 Feb 2019

Abstract excerpt

Introduction: Microsatellite instability (MSI) is a hallmark of defective DNA mismatch repair (MMR) of genes especially MLH1 and MSH2. It is frequently involved in the carcinogenesis of various tumours including gastric cancer (GC). However, MSI in GCs have not been reported in Malaysia before. Objective: This study was conducted to determine the microsatellite instability (MSI) status in gastric cancer by...

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PMID: 30803214
DOI: 10.31557/apjcp.2019.20.2.509

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