Article
Clinicopathologic characteristics and outcomes of gastric cancers with the MSI-H phenotype.
Journal of surgical oncology - 1 Mar 2009
Seo Hyung Min, Chang Yeon Soo, Joo Sun Hyung, Kim Youn Wha, Park Yong-Koo, Hong Sung Wha, Lee Suk-Hwan
Abstract excerpt
OBJECTIVES: We examined the correlation between microsatellite instability (MSI) status and the clinicopathological features and prognostic value in gastric cancer and compared the efficacy of immunohistochemical staining for hMLH1 and hMSH2 with a polymerase chain reaction (PCR)-based test. METHODS: MSI status was examined in 328 consecutive gastric adenocarcinomas using tissue preserved in paraffin blocks. DNA...
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