Article
Modest implication of interleukin-6 promoter polymorphisms in longevity.
Mechanisms of ageing and development - 1 May 2004
Christiansen L, Bathum L, Andersen-Ranberg K, Jeune B, Christensen K
Abstract excerpt
The multifunctional interleukin-6 has been suggested to contribute to a chronic low-grade inflammatory status, thereby conferring susceptibility to age-related pathological conditions as well as functional decline and increased mortality. Several polymorphisms have been identified in the interleukin-6 promoter, but investigation of the effect of these on interleukin-6 levels and disease susceptibility have led to...
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