Article
Distributions of interleukin-6 (IL-6) promoter and metallothionein 2A (MT2A) core promoter region gene polymorphisms and their associations with aging in Turkish population.
Archives of gerontology and geriatrics - 1 Jan 2000
Kayaaltı Zeliha, Sahiner Levent, Durakoğlugil M Emre, Söylemezoğlu Tülin
Abstract excerpt
Aging is determined as the product of an interaction among genetic, environmental and lifestyle factors. As interleukin-6 (IL-6) and metallothioneins (MTs) are related to inflammation and oxidative stress response, their genes are appropriate candidate for aging, age related diseases and infections. The aim of this study was to investigate the association between the IL-6 -174 G/C promoter region and MT2A -5 A/G...
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