Article
Structural tolerance of bacterial autotransporters for folded passenger protein domains.
Molecular microbiology - 1 May 2004
Veiga Esteban, de Lorenzo Víctor, Fernández Luis Angel
Abstract excerpt
In this report we investigate the capacity of bacterial autotransporters (AT) to translocate folded protein domains across the outer membrane (OM). Polypeptides belonging to the AT family contain a C-terminal domain that supports the secretion of the N-domain (the passenger) across the OM of Gram-negative bacteria. Despite some controversial data, it has been widely accepted that N-passenger domains of AT must be...
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