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Article

Probing secretion and translocation of a beta-autotransporter using a reporter single-chain Fv as a cognate passenger domain.

Molecular microbiology - 1 Sept 1999

Veiga E, de Lorenzo V, Fernández L A

Abstract excerpt

The mechanism of protein secretion mediated by the beta-domain of the Neisseria gonorrhoeae IgA protease, a paradigm of a family of secreted polypeptides of Gram-negative bacteria called autotransporters, has been examined using a single-chain antibody (scFv) as a reporter passenger domain to monitor the translocation process. Fusion of a scFv to the beta-module of the IgA protease allowed us to investigate the...

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Identifiers

PMID: 10510237
DOI: 10.1046/j.1365-2958.1999.01571.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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