Article
Crystal structure of the passenger domain of the Escherichia coli autotransporter EspP.
Journal of molecular biology - 11 Nov 2011
Khan Shekeb, Mian Hira S, Sandercock Linda E, Chirgadze Nickolay Y, Pai Emil F
Abstract excerpt
Autotransporters represent a large superfamily of known and putative virulence factors produced by Gram-negative bacteria. They consist of an N-terminal "passenger domain" responsible for the specific effector functions of the molecule and a C-terminal "β-domain" responsible for translocation of the passenger across the bacterial outer membrane. Here, we present the 2.5-Å crystal structure of the passenger domain...
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