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Article

BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas.

The Journal of clinical endocrinology and metabolism - 1 May 2004

Puxeddu Efisio, Moretti Sonia, Elisei Rossella, Romei Cristina, Pascucci Raffaela, Martinelli Marco, Marino Cecilia, Avenia Nicola, Rossi Esther Diana, Fadda Guido, Cavaliere Antonio, Ribacchi Rodolfo, Falorni Alberto, Pontecorvi Alfredo, Pacini Furio, Pinchera Aldo, Santeusanio Fausto

Abstract excerpt

Activating mutations of BRAF have been identified in a variety of human cancers, most notably melanomas and papillary thyroid carcinomas (PTCs). The aim of the present study was to disclose the role of BRAF mutations in thyroid carcinoma development. Seventy-two thyroid tumors, including 60 PTCs, six follicular adenomas, five follicular carcinomas, and one anaplastic carcinoma, were studied. BRAF mutation...

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Source

Identifiers

PMID: 15126572
DOI: 10.1210/jc.2003-031425

Genes

BRAF
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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BRAF(V599E) mutation is the leading genetic event in adult sporadic papillary thyroid carcinomas.PMID 15126572Read ↗

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