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Article

Oncogenic alterations in papillary thyroid cancers of young patients.

Thyroid : official journal of the American Thyroid Association - 1 Jan 2012

Sassolas Geneviève, Hafdi-Nejjari Zakia, Ferraro Angelo, Decaussin-Petrucci Myriam, Rousset Bernard, Borson-Chazot Françoise, Borbone Eleonora, Berger Nicole, Fusco Alfredo

Abstract excerpt

BACKGROUND: Papillary thyroid carcinoma (PTC) in young people usually has an aggressive initial presentation, though a good general prognosis despite recurrences in 10%-20% of patients. A number of genetic alterations that activate the mitogen-activated protein kinase (MAPK) pathway have been found in PTC. Some of these alterations have been identified as prognostic factors of PTC in adults. The objective of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mitogen-Activated Protein Kinases

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Source

Identifiers

PMID: 22150560
DOI: 10.1089/thy.2011.0215

Genes

BRAF
RET

Provenance

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