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Article

BRAF mutations in an Italian cohort of thyroid cancers.

Clinical endocrinology - 1 Aug 2004

Fugazzola Laura, Mannavola Deborah, Cirello Valentina, Vannucchi Guia, Muzza Marina, Vicentini Leonardo, Beck-Peccoz Paolo

Abstract excerpt

OBJECTIVE: Recently, a somatic point mutation of the BRAF gene (V599E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (about 25-70%) in different series from USA, Japan, Portugal and Ukraine. DESIGN: In the present study, the genetic analysis of BRAF in an Italian cohort of 65 thyroid tumours with corresponding normal tissues and 21 thyroid...

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Topics

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

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Share to DNA, Neoplasm

Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Neoplasms

Source

Identifiers

PMID: 15272920
DOI: 10.1111/j.1365-2265.2004.02089.x

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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