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Article

BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma.

Clinical endocrinology - 1 Apr 2008

Costa Angela M, Herrero Agustín, Fresno Manuel F, Heymann Jonas, Alvarez José Antonio, Cameselle-Teijeiro Jose, García-Rostán Ginesa

Abstract excerpt

PURPOSE: BRAF(V600E) mutation represents the most common oncogenic event in sporadic papillary thyroid cancer (PTC). There are, however, significant discrepancies regarding the overall frequency, its prevalence in PTC-variants, and its relationship with clinico-pathological parameters of poor outcome. Moreover, the impact of BRAF(V600E) mutants on tumour-related patient's death has not been evaluated. DESIGN: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18070147
DOI: 10.1111/j.1365-2265.2007.03077.x

Genes

BRAF

Variants

Provenance

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