Article
The selective values of alleles in a molecular network model are context dependent.
Genetics - 1 Apr 2004
Peccoud Jean, Velden Kent Vander, Podlich Dean, Winkler Chris, Arthur Lane, Cooper Mark
Abstract excerpt
Classical quantitative genetics has applied linear modeling to the problem of mapping genotypic to phenotypic variation. Much of this theory was developed prior to the availability of molecular biology. The current understanding of the mechanisms of gene expression indicates the importance of nonlinear effects resulting from gene interactions. We provide a bridge between genetics and gene network theories by...
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