Article
Dissecting dynamic genetic variation that controls temporal gene response in yeast.
PLoS computational biology - 1 Dec 2014
Brodt Avital, Botzman Maya, David Eyal, Gat-Viks Irit
Abstract excerpt
Inter-individual variation in regulatory circuits controlling gene expression is a powerful source of functional information. The study of associations among genetic variants and gene expression provides important insights about cell circuitry but cannot specify whether and when potential variants dynamically alter their genetic effect during the course of response. Here we develop a computational procedure that...
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