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Article

Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast.

Nature genetics - 1 Apr 2017

Forsberg Simon K G, Bloom Joshua S, Sadhu Meru J, Kruglyak Leonid, Carlborg Örjan

Abstract excerpt

Experiments in model organisms report abundant genetic interactions underlying biologically important traits, whereas quantitative genetics theory predicts, and data support, the notion that most genetic variance in populations is additive. Here we describe networks of capacitating genetic interactions that contribute to quantitative trait variation in a large yeast intercross population. The additive variance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28250458
DOI: 10.1038/ng.3800
PMCID: PMC5459553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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