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Article

Cancer predisposition in mice deficient for the metastasis-associated Mts1(S100A4) gene.

Oncogene - 29 Apr 2004

EL Naaman Christina, Grum-Schwensen Birgitte, Mansouri Ahmed, Grigorian Mariam, Santoni-Rugiu Eric, Hansen Thomas, Kriajevska Marina, Schafer Beat W, Heizmann Claus W, Lukanidin Eugene, Ambartsumian Noona

Abstract excerpt

Metastasis-promoting Mts1(S100A4) protein belongs to the S100 family of Ca(2+)-binding proteins. A mouse strain with a germ-line inactivation of the S100A4 gene was generated. The mice were viable and did not display developmental abnormalities in the postnatal period. However, an abnormal sex ratio was observed in the litters with the S100A4-/- genotype, raising the possibility of a certain level of embryonic...

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PMID: 15116098
DOI: 10.1038/sj.onc.1207420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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