Article
Effect of mts1 (S100A4) expression on the progression of human breast cancer cells.
International journal of cancer - 17 Sept 1996
Grigorian M, Ambartsumian N, Lykkesfeldt A E, Bastholm L, Elling F, Georgiev G, Lukanidin E
Abstract excerpt
The mts1 (S100A4) gene, encoding a Ca(2+)-binding protein of the S-100 subfamily, is involved in the control of tumor metastasis in some murine tumor cell lines. To further analyze its role, we transfected hormone-responsive human breast cancer MCF-7 cells with the mts1 gene under the control of a strong constitutive promoter. All of the 3 tested clones (MCF-7/mts1) producing Mts1 protein acquired an ability for...
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