Article
The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression.
European journal of cancer (Oxford, England : 1990) - 1 Nov 2016
Atlasi Yaser, Noori Rubina, Marolin Ivana, Franken Patrick, Brandao Joana, Biermann Katharina, Collini Paola, Grigorian Mariam, Lukanidin Eugene, Ambartsumian Noona, Fodde Riccardo
Abstract excerpt
INTRODUCTION: S100a4 is a calcium-binding protein belonging to the family of S100-proteins, highly expressed in different stromal cell types. S100A4 has been reported as a prognostic marker in colorectal cancer in association with tumour progression and metastasis. METHODS: In this study, we analysed the in vivo role of S100a4 in intestinal tumour initiation and progression using different transgenic and knockout...
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