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Roles of S100 family members in drug resistance in tumors: Status and prospects

22 Apr 2020

Abstract excerpt

Chemotherapy and targeted therapy can significantly improve survival rates in cancer, but multiple drug resistance (MDR) limits the efficacy of these approaches. Understanding the molecular mechanisms underlying MDR is crucial for improving drug efficacy and clinical outcomes of patients with cancer. S100 proteins belong to a family of calcium-binding proteins and have various functions in tumor development....

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PMID: 32335300
DOI: 10.1016/j.biopha.2020.110156

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