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Article

Arg257Cys polymorphism of CYP2A13 in a Chinese population.

Clinica chimica acta; international journal of clinical chemistry - 1 May 2004

Cheng Xin-Yuan, Chen Guo-Lin, Zhang Wei-Xia, Zhou Gan, Wang Dan, Zhou Hong-Hao

Abstract excerpt

BACKGROUND: Human cytochrome P450 2A13 (CYP2A13) is involved in the activation of numerous toxicants and carcinogens, especially in the metabolic activation of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a major tobacco-specific carcinogen. A functionally significant coding single nucleotide polymorphism (C3375T) in exon 5 of CYP2A13, which results in an amino acid substitution of Arg 257 to Cys, has...

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PMID: 15115698
DOI: 10.1016/j.cccn.2004.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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