Article
Single nucleotide polymorphisms of the human cyp2a13 gene: evidence for a null allele.
Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2003
Zhang Xiuling, Chen Ying, Liu Yiqin, Ren Xiang, Zhang Qing-Yu, Caggana Michele, Ding Xinxin
Abstract excerpt
Human CYP2A13 is believed to be important in the metabolic activation of tobacco-specific nitrosamines in the respiratory tract; therefore, genetic polymorphisms of the CYP2A13 gene may be associated with interindividual differences in the risks of tobacco-related tumorigenesis. Our earlier studi...
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