Article
Genetic polymorphism of the human cytochrome CYP2A13 in a French population: implication in lung cancer susceptibility.
Biochemical and biophysical research communications - 30 Apr 2004
Cauffiez Christelle, Lo-Guidice Jean-Marc, Quaranta Sylvie, Allorge Delphine, Chevalier Dany, Cenée Sylvie, Hamdan Rima, Lhermitte Michel, Lafitte Jean-Jacques, Libersa Christian, Colombel Jean-Frédéric, Stücker Isabelle, Broly Franck
Abstract excerpt
The human cytochrome CYP2A13, which is mainly expressed in the respiratory tract, has been shown to be highly efficient in vitro in the metabolism of tobacco-smoke carcinogens and procarcinogens such as 4-methylnitroso-1-(3-pyridyl)-1-butanone (NNK). In order to investigate the extent of CYP2A13...
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