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Article

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.

Diabetologia - 1 May 2004

Tripathy D, Eriksson K F, Orho-Melander M, Fredriksson J, Ahlqvist G, Groop L

Abstract excerpt

AIMS/HYPOTHESIS: The aim of the study was to evaluate the relationship between insulin sensitivity, beta cell function and glucose tolerance, and its dependence on variants in the newly identified Type 2 diabetes susceptibility gene, calpain-10 ( CAPN10). METHODS: We studied 203 men of the same age but with varying degrees of glucose tolerance. These men participated in (i) an oral glucose tolerance test, (ii) a...

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Source

Identifiers

PMID: 15114470
DOI: 10.1007/s00125-004-1393-8

Genes

CAPN10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.PMID 15114470Read ↗

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