Article
Calpain-10: from genome search to function.
Diabetes/metabolism research and reviews - 1 Jan 2000
Turner Mark D, Cassell Paul G, Hitman Graham A
Abstract excerpt
Calpain-10 (CAPN10) is the first diabetes gene to be identified through a genome scan. Many investigators, but not all, have subsequently found associations between CAPN10 polymorphism and type 2 diabetes (T2D) as well as insulin action, insulin secretion, aspects of adipocyte biology and microvascular function. However, this has not always been with the same single nucleotide polymorphism (SNP) or haplotype or...
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