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Article

Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.

PloS one - 18 Aug 2009

Ling Charlotte, Groop Leif, Guerra Silvia Del, Lupi Roberto

Abstract excerpt

BACKGROUND: Calpain-10 was the first gene to be identified influencing the risk of type 2 diabetes (T2D) by positioning cloning. Studies in beta-cell lines and rodent islets suggest that calpain-10 may act as a regulator of insulin secretion. However, its role in human pancreatic islets remains u...

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Source

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Identifiers

PMID: 19688040
DOI: 10.1371/journal.pone.0006558
PMCID: PMC2719809

Genes

CAPN10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19688040-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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