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Article

Systematic HRAS amplification in ovary-independent mammary tumors: correlation with progressively anaplastic phenotypes.

Cancer research - 15 Nov 1993

Aldaz C M, Gollahon L S, Chen A

Abstract excerpt

Progression of well differentiated rat mammary adenocarcinomas to very anaplastic phenotypes was found to correlate with a systematic and significant amplification of a mutant HRAS allele. Tumors with high amplification levels of this oncogene were analyzed by chromosomal in situ hybridization; in four of the cases the amplified sequences did not reside at the native chromosome 1 locus but were localized in a...

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Identifiers

PMID: 8221670

Genes

HRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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