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Article

Cancer research in rat models.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Szpirer Claude

Abstract excerpt

Rat has been the major model species used in several biomedical fields, notably in drug development and toxicology, including carcinogenicity testing. Rat is also a useful model in basic cancer research. Several rat models of monogenic (Mendelian) human hereditary cancers are available. Some were obtained spontaneously, while others were generated either by mutagenesis of tumor suppressor genes or by transgenesis...

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PMID: 20013251
DOI: 10.1007/978-1-60327-389-3_30

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